BCL-2 Family Proteins Pdf

BCL-2 Family Proteins Pdf

BCL-2 Family Proteins Pdf

BCL-2 Family Proteins Pdf

About the book:

BCL-2 Family Proteins Book

Author: Evripidis Gavathiotis

Series: Methods in Molecular Biology (Book 1877)

Publisher: Humana

Publish date: (December 7, 2018)

ISBN-10: 1493988603

ISBN-13: 978-1493988600

Pages: 360 eBook pages can be different

Language: English

Genres: Biochemistry


This volume explores numerous techniques for the genetic, molecular, biochemical, and structural examination of BCL-2 family proteins and their interactions. The chapters in this book cover topics such as the relevance of BCL-2 proteins in health and disease; evaluating cellular dependencies to specific BCL-2 family proteins; flow-cytometry-based methods for measuring BCL-2 proteins and mitochondrial-based cell death; measuring activity and interactions of BCL-2 family proteins in the presence of mitochondria, artificial membranes or yeast; conformational activation and oligomerization of pro-apoptotic proteins BAX and BAK leading to cytochrome c release and apoptosis; structural and biophysical studies in solution and lipid vesicles using nuclear magnetic resonance, cryo-electron microscopy, fluorescence microscopy and electron paramagnetic resonance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, BCL-2 Family Proteins: Methods and Protocols is a valuable resource to inspire and encourage novice and established scientists to further their research and make new discoveries in this exciting field.

BCL-2 Family Proteins Pdf

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