Systems Chemical Biology Pdf

Systems Chemical Biology Pdf

Systems Chemical Biology Pdf

Systems Chemical Biology Pdf

About the book:

Systems Chemical Biology Book

Author: Slava Ziegler

Publisher: Humana

Publish date: (6 December 2018)

ISBN-10: 1493988905

ISBN-13: 978-1493988907

Pages: 315 eBook pages can be different

Language: English

Genres: Biological Sciences


This volume explores the latest available wet-lab techniques and computational methods to study in-cell small-molecule behavior and interactions with their targets. The chapters in this book discuss topics such as disease-relevant models for chemical biology studies, target engagement using cellular thermal shift assay or bioluminescence resonance energy transfer; visualization of bioactive small molecules Raman microscopy; (phospho) proteomics and transcriptomics for mode-of-action studies, CRISPR / Cas9-based chemogenomic profiling in mammalian cells; predicting drug interactions using computational approaches; comparison of compound-induced profiles using high-content imaging or cancer cell line panels and web-based tools for polypharmacology prediction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Systems Chemical Biology: Methods and Protocols are a valuable resource for novice or expert scientists and researchers trying to initiate or continue their chemical biology studies at a system level.

Systems Chemical Biology Pdf

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